Details for gene set NEUROLOGICAL_SYSTEM

Table: GSEA Results Summary

Dataset	RNR_GSEA_DESEQ2_FC
Phenotype	NoPhenotypeAvailable
Upregulated in class	na_neg
GeneSet	NEUROLOGICAL_SYSTEM_PROCESS
Enrichment Score (ES)	-0.11579542
Normalized Enrichment Score (NES)	-2.607972
Nominal p-value	0.0
FDR q-value	0.002197576
FWER p-Value	0.021

Table: GSEA details [plain text format]
	PROBE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	TAS2R16	21	5.157	0.0016	No
2	RHO	62	2.642	0.0021	No
3	GJA8	92	2.189	0.0032	No
4	OTOR	136	1.914	0.0036	No
5	SST	144	1.881	0.0059	No
6	RIT2	151	1.816	0.0083	No
7	CRYGD	154	1.794	0.0109	No
8	GRM5	156	1.783	0.0136	No
9	HTR2A	241	1.367	0.0117	No
10	CHRNB3	268	1.286	0.0130	No
11	CCKBR	274	1.281	0.0154	No
12	CHRNA6	303	1.200	0.0166	No
13	SLC6A4	317	1.162	0.0186	No
14	GUCA1C	346	1.110	0.0198	No
15	TAS2R3	377	1.052	0.0209	No
16	MTNR1B	414	1.008	0.0216	No
17	GRM1	470	0.943	0.0213	No
18	SFRP5	483	0.929	0.0234	No
19	RP1	485	0.928	0.0261	No
20	GAD2	551	0.830	0.0252	No
21	PNOC	558	0.818	0.0276	No
22	PAX3	567	0.804	0.0299	No
23	GRIK2	616	0.756	0.0300	No
24	OCLM	645	0.731	0.0312	No
25	CDS1	646	0.731	0.0339	No
26	KCNIP1	662	0.713	0.0358	No
27	POU6F2	672	0.708	0.0380	No
28	CHRNE	684	0.697	0.0401	No
29	GLRA1	717	0.667	0.0411	No
30	GRM8	778	0.623	0.0405	No
31	OMP	820	0.612	0.0410	No
32	GALR3	910	0.567	0.0388	No
33	MYO3A	917	0.562	0.0412	No
34	DRD1	924	0.558	0.0436	No
35	CRX	942	0.550	0.0454	No
36	COLQ	991	0.523	0.0455	No
37	CARTPT	1008	0.513	0.0473	No
38	GPR98	1064	0.495	0.0470	No
39	SLC1A2	1081	0.491	0.0489	No
40	KCNQ5	1097	0.484	0.0508	No
41	AMPH	1110	0.476	0.0528	No
42	PCDH15	1151	0.454	0.0534	No
43	GDNF	1153	0.453	0.0560	No
44	KCND2	1197	0.438	0.0564	No
45	LUM	1241	0.427	0.0567	No
46	CHRNA7	1298	0.405	0.0564	No
47	HTR1D	1309	0.401	0.0586	No
48	SYN3	1343	0.389	0.0595	No
49	EFEMP1	1362	0.383	0.0612	No
50	CRYBA1	1366	0.381	0.0638	No
51	KRT12	1370	0.380	0.0663	No
52	DIAPH1	1455	0.356	0.0644	No
53	HTR1E	1492	0.349	0.0652	No
54	AIPL1	1581	0.331	0.0631	No
55	NDP	1582	0.331	0.0658	No
56	HTR7	1654	0.318	0.0646	No
57	CLRN1	1658	0.318	0.0672	No
58	GNAT1	1690	0.313	0.0682	No
59	SLC6A1	1698	0.312	0.0705	No
60	GABRR1	1737	0.304	0.0712	No
61	PDE6B	1745	0.302	0.0735	No
62	CRYM	1829	0.288	0.0717	No
63	SLC26A5	1830	0.288	0.0744	No
64	MBP	1833	0.287	0.0770	No
65	SLC26A4	1941	0.268	0.0739	No
66	UTS2	2089	0.252	0.0685	No
67	GRIN2A	2109	0.250	0.0702	No
68	PDE7B	2122	0.248	0.0723	No
69	KCNA1	2150	0.245	0.0735	No
70	TAS2R43	2194	0.240	0.0739	No
71	SCN2B	2199	0.239	0.0764	No
72	OPN1MW	2210	0.237	0.0785	No
73	CHML	2241	0.235	0.0796	No
74	PDE6A	2278	0.230	0.0804	No
75	GABRB2	2287	0.229	0.0826	No
76	COL4A4	2328	0.226	0.0832	No
77	CYP1B1	2422	0.216	0.0808	No
78	ALDH7A1	2450	0.214	0.0820	No
79	EYA4	2479	0.211	0.0832	No
80	KIF5A	2553	0.205	0.0819	No
81	DHRS3	2556	0.205	0.0845	No
82	CDH23	2583	0.203	0.0858	No
83	CTNS	2655	0.197	0.0847	No
84	RDH10	2661	0.196	0.0871	No
85	AKAP9	2670	0.196	0.0894	No
86	CHM	2677	0.195	0.0918	No
87	GRIK4	2687	0.194	0.0940	No
88	GABARAP	2702	0.193	0.0959	No
89	KCNMA1	2740	0.190	0.0966	No
90	STX1B	2869	0.181	0.0923	No
91	GPR143	2908	0.178	0.0930	No
92	PLP1	2921	0.177	0.0950	No
93	NOVA1	2946	0.175	0.0964	No
94	AKAP5	3002	0.173	0.0962	No
95	NF1	3060	0.169	0.0957	No
96	HOMER1	3260	0.157	0.0876	No
97	COL4A3	3265	0.157	0.0901	No
98	CRYBB1	3269	0.156	0.0926	No
99	DOC2A	3294	0.155	0.0940	No
100	IQCB1	3317	0.154	0.0955	No
101	KIF1B	3377	0.152	0.0950	No
102	KCNMB2	3383	0.152	0.0975	No
103	TECTA	3418	0.150	0.0983	No
104	NPHP3	3436	0.149	0.1001	No
105	HCRTR1	3447	0.148	0.1023	No
106	KCNN3	3517	0.144	0.1012	No
107	SLC5A7	3589	0.141	0.1000	No
108	MYO6	3620	0.139	0.1011	No
109	NLGN1	3765	0.133	0.0960	No
110	SLC1A1	3774	0.132	0.0982	No
111	ALDH9A1	3819	0.130	0.0985	No
112	GNAS	3869	0.128	0.0986	No
113	ATXN7	3946	0.125	0.0971	No
114	ATXN3	4011	0.122	0.0963	No
115	SLIT2	4095	0.119	0.0945	No
116	SCN1B	4099	0.118	0.0971	No
117	RIMS1	4225	0.114	0.0929	No
118	CD9	4239	0.113	0.0949	No
119	EYA3	4328	0.111	0.0928	No
120	APBA1	4342	0.110	0.0949	No
121	IMPG1	4384	0.109	0.0953	No
122	SNCAIP	4533	0.104	0.0899	No
123	TACSTD2	4839	0.093	0.0760	No
124	USH2A	4876	0.092	0.0767	No
125	EYA1	4909	0.091	0.0777	No
126	MYO9A	5037	0.088	0.0734	No
127	BSN	5066	0.087	0.0746	No
128	PDE6H	5073	0.087	0.0770	No
129	MAPK1	5144	0.085	0.0759	No
130	UBB	5276	0.081	0.0714	No
131	KCNE1	5308	0.080	0.0725	No
132	OAT	5477	0.076	0.0660	No
133	PPARD	5613	0.072	0.0613	No
134	UBR3	5636	0.072	0.0628	No
135	DFNB31	5841	0.066	0.0544	No
136	GRIA1	6038	0.061	0.0463	No
137	NRL	6149	0.059	0.0430	No
138	NPTN	6208	0.057	0.0426	No
139	DFNA5	6243	0.057	0.0434	No
140	RTP4	6267	0.056	0.0449	No
141	GLRB	6295	0.055	0.0461	No
142	MYO15A	6358	0.054	0.0455	No
143	ABLIM1	6378	0.053	0.0471	No
144	SEPT5	6401	0.053	0.0486	No
145	RABGGTB	6413	0.052	0.0508	No
146	SRI	6470	0.051	0.0504	No
147	TBL1X	6499	0.050	0.0516	No
148	TAS2R5	6613	0.048	0.0481	No
149	YWHAG	6629	0.048	0.0500	No
150	CHRNA5	6729	0.045	0.0473	No
151	KIFC3	6739	0.045	0.0495	No
152	KCNMB1	6935	0.041	0.0416	No
153	SHROOM4	7037	0.039	0.0388	No
154	ABCA4	7186	0.035	0.0334	No
155	RDH12	7271	0.034	0.0315	No
156	TAS2R4	7298	0.033	0.0328	No
157	CYB5R4	7574	0.027	0.0205	No
158	PI4KA	7581	0.027	0.0228	No
159	OPA1	7665	0.025	0.0210	No
160	EML2	7831	0.023	0.0147	No
161	HTR1B	7869	0.022	0.0154	No
162	RP2	7923	0.021	0.0152	No
163	DRD2	7972	0.020	0.0153	No
164	SCN10A	8141	0.017	0.0088	No
165	CACNA1F	8144	0.017	0.0114	No
166	DRD4	8250	0.014	0.0084	No
167	FXN	8471	0.010	-0.0009	No
168	OPA3	8604	0.007	-0.0055	No
169	COL18A1	8694	0.005	-0.0076	No
170	HPRT1	8699	0.005	-0.0051	No
171	TRPV2	8827	0.003	-0.0093	No
172	KCNQ3	8894	0.001	-0.0102	No
173	WFS1	9091	-0.003	-0.0183	No
174	STRN4	9113	-0.003	-0.0167	No
175	DNAJC19	9161	-0.004	-0.0165	No
176	HCRT	9235	-0.006	-0.0178	No
177	KCNMB4	9277	-0.006	-0.0174	No
178	WDR1	9290	-0.007	-0.0153	No
179	EIF2B5	9324	-0.008	-0.0144	No
180	SYN1	9364	-0.008	-0.0138	No
181	TGFBI	9551	-0.012	-0.0213	No
182	PRPH2	9608	-0.013	-0.0216	No
183	YWHAH	9617	-0.013	-0.0193	No
184	PCDHB10	9794	-0.017	-0.0263	No
185	CNTN4	9797	-0.017	-0.0236	No
186	CHRNA1	9861	-0.018	-0.0244	No
187	PDC	10015	-0.021	-0.0300	No
188	GPR176	10154	-0.023	-0.0349	No
189	GRIK1	10239	-0.025	-0.0368	No
190	C5AR1	10286	-0.026	-0.0366	No
191	SNAPIN	10301	-0.026	-0.0346	No
192	EIF2B4	10302	-0.026	-0.0319	No
193	MYCBPAP	10303	-0.026	-0.0292	No
194	DTNA	10405	-0.028	-0.0320	No
195	TRPC3	10477	-0.029	-0.0332	No
196	MYO1A	10494	-0.030	-0.0313	No
197	SORD	10608	-0.032	-0.0348	No
198	GCH1	10666	-0.033	-0.0352	No
199	GRM2	10857	-0.038	-0.0429	No
200	TGFB2	10886	-0.039	-0.0417	No
201	COCH	10950	-0.040	-0.0424	No
202	VIPR1	10969	-0.041	-0.0407	No
203	PMP22	10970	-0.041	-0.0380	No
204	CRYZ	10994	-0.041	-0.0365	No
205	SOD1	11052	-0.043	-0.0369	No
206	PITPNA	11286	-0.049	-0.0470	No
207	NDUFB9	11314	-0.049	-0.0457	No
208	PDE6C	11316	-0.049	-0.0431	No
209	MYO7A	11553	-0.054	-0.0533	No
210	AMIGO1	11558	-0.055	-0.0508	No
211	PXK	11995	-0.065	-0.0719	No
212	OPN1SW	12034	-0.066	-0.0713	No
213	TIMM10	12215	-0.070	-0.0784	No
214	SLC1A3	12319	-0.072	-0.0813	No
215	RAPSN	12335	-0.073	-0.0795	No
216	MPZ	12500	-0.078	-0.0857	No
217	PDE6D	12639	-0.082	-0.0906	No
218	BAIAP3	12684	-0.083	-0.0902	No
219	TIMM8B	12833	-0.087	-0.0956	No
220	RDH5	12927	-0.090	-0.0980	No
221	EIF2B2	12953	-0.090	-0.0967	No
222	PITPNM1	12974	-0.091	-0.0950	No
223	IMPG2	13048	-0.093	-0.0963	No
224	RAB3A	13121	-0.096	-0.0975	No
225	NPTX1	13133	-0.096	-0.0954	No
226	GJA3	13224	-0.099	-0.0976	No
227	PCDHB4	13258	-0.100	-0.0967	No
228	UNC119	13291	-0.101	-0.0958	No
229	PCDHB6	13295	-0.101	-0.0932	No
230	BEST1	13308	-0.102	-0.0911	No
231	PCDHB16	13463	-0.107	-0.0969	No
232	KCNQ1	13522	-0.108	-0.0973	No
233	CABP4	13553	-0.110	-0.0962	No
234	GAD1	13556	-0.110	-0.0936	No
235	ROM1	13633	-0.113	-0.0951	No
236	TIMM9	13647	-0.113	-0.0931	No
237	NMUR1	13663	-0.114	-0.0912	No
238	CHRNB1	13697	-0.115	-0.0903	No
239	TYR	13742	-0.117	-0.0900	No
240	SYPL1	13746	-0.117	-0.0874	No
241	CNP	13747	-0.117	-0.0847	No
242	RPGR	13776	-0.119	-0.0835	No
243	ZNF354A	13957	-0.126	-0.0906	No
244	PAX6	13970	-0.126	-0.0886	No
245	GRM3	14032	-0.130	-0.0892	No
246	TULP2	14043	-0.131	-0.0870	No
247	COL11A1	14061	-0.132	-0.0853	No
248	TIMM13	14218	-0.139	-0.0911	No
249	CORT	14363	-0.147	-0.0962	No
250	DLG4	14501	-0.154	-0.1010	No
251	PCDHB3	14620	-0.159	-0.1048	No
252	RABGGTA	14633	-0.160	-0.1027	No
253	GUCA1A	14677	-0.163	-0.1023	No
254	TAS2R14	14699	-0.164	-0.1008	No
255	PCDHB13	14755	-0.168	-0.1011	No
256	PDE6G	14814	-0.172	-0.1015	No
257	MAL	14829	-0.173	-0.0996	No
258	LPAR3	14884	-0.177	-0.0998	No
259	OPRL1	14942	-0.181	-0.1002	No
260	OPN1LW	14959	-0.182	-0.0984	No
261	ADORA2A	15000	-0.185	-0.0979	No
262	PRR4	15128	-0.195	-0.1021	No
263	KCNC4	15135	-0.196	-0.0997	No
264	CRYBB2	15151	-0.197	-0.0978	No
265	CNGA1	15175	-0.199	-0.0964	No
266	ARR3	15296	-0.209	-0.1002	No
267	TAS1R3	15299	-0.209	-0.0976	No
268	GCHFR	15514	-0.229	-0.1066	No
269	CHRNA10	15683	-0.247	-0.1131	Yes
270	QPRT	15695	-0.248	-0.1110	Yes
271	HTR1F	15742	-0.255	-0.1108	Yes
272	NTSR2	15773	-0.259	-0.1097	Yes
273	KCNMB3	15819	-0.265	-0.1094	Yes
274	HCRTR2	15851	-0.269	-0.1084	Yes
275	GJB2	15865	-0.271	-0.1064	Yes
276	VSX1	15868	-0.271	-0.1038	Yes
277	ATP6V0A4	15925	-0.278	-0.1042	Yes
278	CRYAA	15966	-0.283	-0.1036	Yes
279	PCDHB5	15967	-0.283	-0.1009	Yes
280	RDH8	16036	-0.291	-0.1019	Yes
281	RPE65	16043	-0.292	-0.0995	Yes
282	FSCN2	16072	-0.295	-0.0983	Yes
283	PCDHB14	16101	-0.300	-0.0972	Yes
284	POU4F3	16119	-0.303	-0.0954	Yes
285	HAP1	16190	-0.315	-0.0965	Yes
286	SYT5	16211	-0.319	-0.0949	Yes
287	PCDHB11	16244	-0.326	-0.0939	Yes
288	KCNQ4	16279	-0.330	-0.0930	Yes
289	NQO1	16487	-0.374	-0.1017	Yes
290	GALR2	16500	-0.377	-0.0996	Yes
291	CRYBB3	16529	-0.383	-0.0984	Yes
292	OTOF	16542	-0.386	-0.0964	Yes
293	RRH	16653	-0.411	-0.0997	Yes
294	CRH	16671	-0.418	-0.0979	Yes
295	GABRR2	16714	-0.430	-0.0975	Yes
296	GUCY2D	16779	-0.447	-0.0982	Yes
297	DBH	16796	-0.452	-0.0964	Yes
298	OPRM1	16799	-0.453	-0.0938	Yes
299	RAX	16828	-0.462	-0.0926	Yes
300	NTSR1	16833	-0.464	-0.0901	Yes
301	PCDHB2	16897	-0.479	-0.0908	Yes
302	NMUR2	16900	-0.480	-0.0882	Yes
303	RTP3	16910	-0.482	-0.0860	Yes
304	ATP6V1B1	16913	-0.482	-0.0834	Yes
305	AOC2	16930	-0.486	-0.0816	Yes
306	CBLN1	16950	-0.490	-0.0799	Yes
307	GUCY2F	16976	-0.498	-0.0785	Yes
308	OPN4	16993	-0.502	-0.0767	Yes
309	GHRL	17024	-0.509	-0.0756	Yes
310	RLBP1	17032	-0.511	-0.0733	Yes
311	APOE	17052	-0.519	-0.0716	Yes
312	TAS1R1	17079	-0.527	-0.0703	Yes
313	SLC1A6	17104	-0.537	-0.0689	Yes
314	GRIA2	17150	-0.556	-0.0687	Yes
315	SYT1	17164	-0.563	-0.0667	Yes
316	HRH3	17186	-0.572	-0.0651	Yes
317	CNGB3	17198	-0.579	-0.0630	Yes
318	KCNN1	17203	-0.581	-0.0605	Yes
319	CALY	17239	-0.598	-0.0597	Yes
320	NPBWR1	17252	-0.603	-0.0576	Yes
321	GRK1	17282	-0.619	-0.0565	Yes
322	SAG	17295	-0.626	-0.0544	Yes
323	CPLX1	17296	-0.627	-0.0517	Yes
324	TULP1	17299	-0.628	-0.0491	Yes
325	RCVRN	17319	-0.644	-0.0474	Yes
326	ATP2B2	17344	-0.653	-0.0460	Yes
327	GABBR2	17458	-0.711	-0.0495	Yes
328	VAX2	17468	-0.718	-0.0473	Yes
329	CRYBA4	17483	-0.724	-0.0453	Yes
330	HTR6	17531	-0.751	-0.0452	Yes
331	CALCA	17537	-0.756	-0.0427	Yes
332	NTF4	17538	-0.757	-0.0400	Yes
333	HTR3A	17557	-0.771	-0.0383	Yes
334	GRM4	17584	-0.793	-0.0370	Yes
335	RS1	17615	-0.820	-0.0359	Yes
336	OPRK1	17632	-0.832	-0.0341	Yes
337	PAX2	17646	-0.842	-0.0321	Yes
338	HTR3B	17659	-0.851	-0.0300	Yes
339	SIX3	17694	-0.883	-0.0291	Yes
340	SLC6A5	17702	-0.888	-0.0268	Yes
341	KCNK3	17714	-0.895	-0.0247	Yes
342	TAS1R2	17747	-0.917	-0.0237	Yes
343	USH1C	17763	-0.935	-0.0218	Yes
344	HTR2C	17850	-0.995	-0.0238	Yes
345	CPNE6	17899	-1.036	-0.0237	Yes
346	RGS16	17973	-1.101	-0.0250	Yes
347	KCNQ2	17976	-1.103	-0.0224	Yes
348	RGR	17985	-1.115	-0.0201	Yes
349	GRIN2B	18050	-1.185	-0.0209	Yes
350	NPY	18089	-1.220	-0.0203	Yes
351	CHRNB4	18099	-1.237	-0.0181	Yes
352	CNGB1	18108	-1.256	-0.0158	Yes
353	GRM7	18130	-1.297	-0.0142	Yes
354	CNGA3	18142	-1.310	-0.0121	Yes
355	SLC6A2	18164	-1.373	-0.0105	Yes
356	CACNA1B	18165	-1.376	-0.0078	Yes
357	CHRNA4	18169	-1.385	-0.0053	Yes
358	TAAR5	18200	-1.443	-0.0042	Yes
359	OR1D5	18208	-1.443	-0.0018	Yes
360	CACNA1E	18274	-1.526	-0.0027	Yes
361	PROK2	18307	-1.613	-0.0017	Yes
362	KLK8	18318	-1.642	0.0005	Yes
363	RBP3	18349	-1.756	0.0015	Yes
364	POU3F4	18403	-1.983	0.0013	Yes
365	GJB6	18436	-2.112	0.0023	Yes
366	PRG3	18482	-2.494	0.0026	Yes
367	USH1G	18512	-2.856	0.0037	Yes
368	CRYGA	18546	-3.742	0.0046	Yes